Blog
Method notes, results and company news from Novasign.
BiotechnologyHybrid ModelingOct 15, 2020Novasign Soft Sensing Technology at Siemens’ LivingLab
Innovative tools to monitor important upstream bioprocess variables in real-time, such as biomass, are of high interest for manufacturers. Typically, to get these values, a sample must be drawn, processed, and analyzed. These steps lead to an inevitable time delay, which makes this desired…
Bioprocess DevelopmentOct 8, 2020The Future of Bioprocess Development - A Panel Discussion with Leading Experts
The emerging COVID-19 pandemic did oblige us to rearrange over habits and routines and presented bioprocess development with new challenges to master, i.e., current working procedures state-of-the-art techniques must be reshaped to put bioprocessing into a new light. Over the last months, many…
BioprocessJun 22, 2020Intensified DoE and hybrid modeling accelerate upstream process characterization
Process characterization is necessary for the biopharmaceutical industry to guarantee a robust and uniform product quality output. Typically, two elements are applied to accomplish this task:
BioprocessMay 27, 2020Hybrid Models facilitate Scale-Up and Digital Twins for tangential flow filtration
The benefits of bioprocess modeling are well known:
Bioprocess DevelopmentBiotechnologyApr 3, 2020COVID-19: An example of why we need robust and fast process development
The current worldwide situation regarding the COVID-19 pandemic has shown all of us how vulnerable our daily life can be. In the case of such an unpredicted event, everyone must make trade-offs, personal and economic. That is why in such situations it is of the highest priority to react fast and…
Bioprocess DevelopmentBiotechnologyMar 18, 2020COVID-19, Home Office and a New Toolbox Release
Due to the COVID-19 outbreak, the Austrian government decided to minimize unnecessary human interaction. These actions will reduce the number of new infections and flattens the curve, providing enough time for the health system to cope with these new unmet challenges. Hence, Novasign also followed…
Bioprocess DevelopmentBiotechnologyOct 18, 2019The Hybrid Modeling Summer School 2019
From the 25th to the 27th of September, Novasign co-hosted the 4th hybrid modeling summer school in Lisbon, Portugal. After a very detailed introduction to hybrid modeling by Prof. Rui Oliveira and Moritz von Stosch, the 41 participants were introduced to the pre-release Novasign hybrid modeling…
Aug 27, 2019Beyond Static Process Descriptions
Have you ever used design of experiments (DoE) tools to describe your upstream bioprocess? If so you most definitely have missed the essentials of the process: the dynamics!
Apr 9, 2019Novasign at the Vienna City Marathon 2019
Last Sunday, we participated in the 36th Vienna City Marathon (VCM). The VCM takes place each spring since 1984 and is Austria’s biggest sports event with about 40.000 runners from 125 nations. The course led to Vienna's most impressive sites like the Vienna Secession, the castle Schönbrunn and the…
BiotechnologyHybrid ModelingMar 27, 2019Bioprocessing Europe Lisbon
Last week we have been to Bioprocessing Europe in Lisbon. The conference was organized in a brought manner, offering both, an up- and downstream processing stream, as well as a gene and cell therapy stream. With more than 100 experts presenting their current bleeding and cutting edge technology,…
BiotechnologyFDANov 7, 2018Reducing the costs of biopharmaceuticals: a bioprocess development approach
In 2018 the generated revenue by biopharmaceuticals is estimated to be approximately 200 b$! Although this is an incredibly high number, this revenue will only be generated by approximately 20 metric tons of biopharmaceuticals! Or in other words: one gram of biopharmaceutics sells around 10000 €.…
BioprocessBiotechnologyAug 8, 2018Best talk @10th ÖGMBT Annual Meeting
From the 17th to the 20th of September, the 10th ÖGMBT Annual Meeting took place in Vienna. Over 450 participants including employees from large pharmaceutical companies, equipment vendors and students met at the campus of the University of Vienna. They presented the latest results in different…
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